Data Import Examples

Examples demonstrating import of clinical data in CDISC and custom formats.

CDISC Domains

Domain	Description	Use
PC	Pharmacokinetic Concentrations	Observed PK data
EX	Exposure	Dosing records
DM	Demographics	Subject characteristics
VS	Vital Signs	Covariates (weight, etc.)
LB	Lab Results	Biomarkers, renal function

Examples

Example	Description	Directory
Basic PC/EX	Standard PK data import	01_basic_pc_ex
With Infusion	Infusion data from EXDUR	02_with_infusion
XPT Format	SAS transport files	03_xpt_format

Basic Usage

from neopkpd.data import load_cdisc

# Load from CSV files
data = load_cdisc(
    pc="pc.csv",
    ex="ex.csv",
    dm="dm.csv"
)

# Access as NeoPKPD format
print(f"Subjects: {len(data.subjects)}")
print(f"Observations: {len(data.observations)}")
print(f"Doses: {len(data.doses)}")

CDISC to NeoPKPD Mapping

PC Domain

CDISC Variable	NeoPKPD
USUBJID	subject_id
PCTPTNUM / PCELTM	time
PCSTRESN	dv
PCSPEC	compartment
PCLLOQ	lloq

EX Domain

CDISC Variable	NeoPKPD
USUBJID	subject_id
EXSTDTC + EXSTTM	dose_time
EXDOSE	amount
EXDUR	duration (for infusion)
EXROUTE	route

DM Domain

CDISC Variable	NeoPKPD
USUBJID	subject_id
AGE	covariates.age
SEX	covariates.sex
RACE	covariates.race

See Also

• Model Import - NONMEM/Monolix import
• Population Examples - Using covariates