Monolix pk1cpt Import

Import a one-compartment oral model from Monolix project.

Monolix Model

• Structural: lib:oral1_1cpt_kaVCl
• Parameters: ka=1.5 1/h, V=50.0 L, Cl=5.0 L/h
• IIV: ka, V, Cl (log-normal)
• Error: Combined

Files

File	Description
project.mlxtran	Monolix project file
convert.py	Python conversion
expected.json	Expected NeoPKPD spec

Conversion

from neopkpd import import_monolix

model = import_monolix("project.mlxtran")
print(model.spec)

Parameter Mapping

Monolix	NeoPKPD
ka_pop	params.Ka
V_pop	params.V
Cl_pop	params.CL
omega_ka	iiv.omegas.Ka
omega_V	iiv.omegas.V
omega_Cl	iiv.omegas.CL