Skip to content

NONMEM ADVAN4 Import

Import a two-compartment IV bolus model from NONMEM.

NONMEM Model

  • ADVAN: 4 (Two-compartment)
  • TRANS: 4 (CL, V1, Q, V2 parameterization)
  • Parameters: CL=5.0 L/h, V1=10.0 L, Q=2.0 L/h, V2=20.0 L
  • IIV: CL (30% CV), V1 (25% CV)
  • Error: Proportional (15% CV)

Files

File Description
run003.ctl NONMEM control file
convert.py Python conversion
expected.json Expected NeoPKPD spec

Parameter Mapping

NONMEM NeoPKPD
THETA(1) = CL params.CL
THETA(2) = V1 params.V1
THETA(3) = Q params.Q
THETA(4) = V2 params.V2